Clinical Studies
Vagus nerve stimulation (VNS) has become a standard therapeutic option for patients with treatment resistant epilepsy and depression and globally is gaining increasing acceptance. Based on the positive experiences with implantable systems, transcutaneous vagus nerve stimulation (tVNS) was first introduced 20 years ago. The field of tVNS is rapidly expanding since the external stimulation is non-invasive and thus avoids numerous side-effects of invasive VNS; tVNS is easily accessible, less expensive and therefore more readily available than conventional VNS. However, transcutaneous stimulation of the outer ear poses new questions regarding the optimal stimulation site and stimulus parameters as well as the physiology and pathways of transcutaneous auricular VNS. Moreover, therapeutic options and realistically reachable goals of tVNS need to be explored.
During the last 20 years, basic and clinical research has unraveled many of these questions and augmented our understanding of tVNS pathways and physiologic effects. The number of publications increased exponentially within the last three years and continues to grow rapidly. Many questions have been addressed and therapeutic indications beyond the treatment of drug-resistant epilepsy and depression are steadily expanding and continue to be explored.
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Non-Surgical Treatment
tVNS-L ® offers vagus treatment option in full patient control, which does not require surgery and does not involve invasive risks.
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Remote Delivery
Device delivery, regular follow-up and any update on the therapy are possible remotely without leaving your home.
Minimal Side Effects
tVNS® has minimal side effects compared to drug treatments and invasive treatmens.
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Innovative Technology
With the tVNS® Patient application, you can follow your treatment and share it with your doctor remotely.
More Flexibility
Pacemaker, cerebral shunt, cardiovascular and respiratory diseases are not barriers to try tVNS therapy
Pediatric Flexibility
Approved for children aged 3 and over, can be used from a doctor-approved newborn as there is no invasive intervention
Customized Therapy
tVNS ® is a personalized therapy that can be customized according to the patient's life routines and symptoms.
Easy to Use
tVNS-L ® is easy to use, as small as a smartphone and perfectly suited for everyday life.
More Controlled Life
It can significantly reduce or eliminate symptoms. in this way can provide a more controlled life
tVNS® L is approved for the treatment of the following indications.
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Anxiety
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Asthma
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Atrial Fibrillation
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Autism
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Cognitive Impairment
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Crohn's disease
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Depression
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Epilepsy
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Fibromyalgia
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inflammation
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Migraine
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Parkinson's
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Prader-Willi Syndrome
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Sleeping disorders
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Stroke
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Tinnitus
What is Migraine?
It is a neurological disorder that causes a throbbing, severe headache, often felt intensely on one side of the head. The distinctive features of migraine that distinguish it from other headaches include nausea and vomiting, and sensitivity to sound and light. The pain is so severe that it interferes with the completion of daily activities and leads to limitation. Migraine attacks take the first place among the most important causes of disability and loss of work in developed countries.
Many migraine attacks are seen as a type of "migraine without aura". Other conditions accompanying the headache of migraine patients without aura; nausea, vomiting, sensitivity to light, sound and smell. Migraine patients with aura, on the other hand, may experience "aura" attacks ranging from 5 minutes to 60 minutes before the headache attacks begin.
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Migraine is a genetically inherited disease. In other words, migraine is more common in people with a family history of migraine. Although not in the family, women are at risk for migraine headaches during hormonal transition (adolescence, premenstrual days, menopause) and during the periods when they use birth control pills. . The sensory nerve of our face, cerebral vessels and cerebral cortex is the same. This nerve can also be stimulated in external environment triggers and trigger pain mechanisms in the brain. During migraine, the cerebral vessels first narrow and then expand. The increase in pressure due to enlargement in the brain vessels is the cause of the throbbing finding in the person.