IN EPILEPSY
Treatment Without Drugs or Surgery Is Possible
Clinically proven and patient-friendly, tVNS® is the only approved vagus stimulator for epilepsy worldwide.
Benefits of tVNS® in Epilepsy Treatment
Why tVNS® Therapy?
In epilepsy treatment, the first-line option is usually antiepileptic drugs (AEDs). For many patients, these medications help control seizures. However, long-term drug use can cause serious side effects. Moreover, in about 30% of epilepsy patients, seizures persist despite medication. This condition is known as drug-resistant epilepsy (DRE) and represents a major clinical challenge.
For DRE patients, second-line treatments may include surgical interventions or invasive vagus nerve stimulation (VNS). Yet, these options are not suitable for every patient. Some patients:
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Are not medically eligible for surgery
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Fear the risks associated with surgery
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Do not want a permanent implant
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Seek alternative solutions with fewer side effects
As a result, there is a growing need for non-invasive, home-based, and personalized treatment approaches. Non-invasive vagus nerve stimulation devices such as tVNS® represent a science-based solution that is pioneering a new era in addressing this unmet need.
Epilepsy is a chronic central nervous system disorder in which abnormal electrical activity in brain cells causes recurring seizures. Seizures can manifest as loss of consciousness, convulsions, sensory changes, or behavioral abnormalities. Approximately 50 million people worldwide live with epilepsy, making it one of the most common neurological disorders.
Antiepileptic drugs (AEDs) are generally used as the first-line treatment for epilepsy. However, approximately 30% of patients with epilepsy do not respond adequately to these treatments. This group is defined as "drug-resistant epilepsy (DRE)." Alternative treatment methods are of great importance for patients with DRE.
Why Are New Approaches Necessary in Epilepsy?
Why Are New Approaches Necessary in Epilepsy?
Drug resistance: Approximately 30% of patients cannot achieve adequate seizure control with medications.
Side effects: Side effects such as drowsiness, loss of concentration, weight gain, and mood swings can negatively impact quality of life.
Long-term use is necessary: Medications are usually used for life and sudden discontinuation may cause an increase in seizures.
High risk: Surgery carries a risk of serious complications such as bleeding, infection, and neurological damage.
Limited suitability: Not all patients are suitable for surgery; surgery cannot be performed, particularly in cases where seizure foci cannot be identified or are widespread.
Long recovery process: Post-operative recovery may result in a temporary decrease in quality of life.
Why Are New Approaches Necessary in Epilepsy?
Why Are New Approaches Necessary in Epilepsy?
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Invasive procedure: The device is surgically implanted in the neck area, which carries surgical risks.
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Permanent implant: Re-surgery is required to remove or replace the device.
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Side effects: Side effects such as hoarseness, throat discomfort, and shortness of breath may occur.
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Treatment: Every change in the implant current requires a hospital visit, and every few years the battery is replaced surgically.
Why Are New Approaches Necessary in Epilepsy?
Patients who cannot be adequately controlled with medications (IDE)
Patients who want to reduce their medication use to avoid long-term side effects of medications
Individuals who are not suitable for surgical intervention
Patients who wish to experience the mood, mental, and motor development effects of vagus nerve stimulation other than seizures
Patients and families seeking non-invasive, at-home therapy