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Changing the World, Changing the Lives In More than 50 Countries of the World With Our 20 Years of Vagus Treatment Experience We Are Here for a Brand New Quality of Life Our tVNS® health solutions help thousands of patients to discover a brand new quality of life. What is tVNS®? tVNS® is a medical device for the treatment of symptoms of sympathovagal imbalance and was specially developed for patients who are not free of symptoms despite drug therapy. tVNS® stimulates the branch of the vagus nerve in the auricle through the skin with gentle electrical impulses. Signals are passed on to the brain via special nerve fibers: first in the brain stem and then in higher centers. The treatment with tVNS® is applied by patients independently. It has been used by thousands of patients and is a treatment with very few side effects. tVNS® is indicated to treat sympathovagal imbalance in the following conditions: ​ ​ Anxiety Migrain Autism Cognitive Impairment Depression Fibromyalgia E p ilepsy Inflammation Pr ader-Willi Syndrome Sleep Disorders Stroke Tinnitus Asthma Crohn's Disease Atrial Fibrillation Parkinson's tVNS® CARE Therapy Tracking​ THE MOST EFFECTIVE WAY TO GET RESULTS FROM tVNS®* For patient-driven medical device treatments that the patient can apply at home without the supervision of a doctor, the most important need for the success of the treatment is the preparation of a protocol specific to the patient's needs and the remote follow-up by the doctor and an expert team to see whether the patient can use the device correctly. tVNS Care®, o ur unique digital health service, where a patient-specific program is prepared based on the protocols of similar patients in more than 50 countries and all details of the treatment can be followed online by our expert teams. Why Treatment with tVNS® Device? Customized Therapy ​ t VNS® therapies are customized for each patient, based on indication and needs, so can provide a unique solution for every patient. More Flexibility ​ ​ With the help of the rechargeable battery, it allows several different parameters and treatment protocols. Innovative App ​ With the tVNS® Patient App you can track your treatment, share results with your doctor and get therapy consultation wherever you are R emote Training tVNS® allows remote delivery and training without any need for travel, so that any patient can start using the therapy on their home No Surg ery ​ tVNS® enables non-surgical vagus nerve stimulation with full patient control and no invasive- risks Few Side Effects ​ tVNS® has very few side effects compared to drugs and invasive treatments, and easily tolarable. Pediatric Flexibility ​ It can be used safely at any age from newborn babies with the approval of the doctor. Easy to Use ​ tVNS® is easy to use, as small as a smartphone and can be easily integrated into everyday life. tVNS® Hastalarının Tedavi Öyküleri My 7-year-old son with Dravet syndrome had seizure periods that required intensive care treatments every month. We have been using tVNS for 2 years, and we are happy to have a seizure-free life, obtain mental development, and reduction in autism symptoms. Zeliha KORKMAZ, Kayseri, Erciyes University Prof. Dr. Hakan GüMüŞ Download the tVNS ® Patient App Meet the Tele-Medicine Technologies of the Future ​ With the innovative tVNS® patient app, you can track your treatment at any time and share your data with your doctor. In addition, the tVNS® patient app enables us to continuously improve our technology and optimize your treatment. The tVNS® Patient App is available now in the Google Play Store and in the Apple App Store (EU-only). ​ ​ How does tVNS® work? You can use tVNS® anytime, anywhere. It is easy to use, portable and discrete. ​ tVNS® activates special nerve fibers through gentle electrical impulses (neurostimulation) via an ear electrode on the ear, stimulating the branch of the vagus nerve in the auricle through the skin, by sending nerve signals to the brainstem and the higher centers. This alleviates symptoms of sympathovagal imbalance, for example reducing seizures in epilepsy. Watch this short video to learn more about our tVNS® health solutions and how tVNS® works. ​ ​ Contact us blog tVNS Parkinson Testimonial International Autonomic Neuroscience Society Journal: "tVNS Special Issue" tVNS vagus therapy has started in our first pediatric resistant epilepsy patient in Turkey NP Istanbul Brain Hospital Multidisciplinary Meetings (23/02/2021) Contact us Name Surname Where did you hear about us? Internet search tVNS social media (Facebook, instagram) My Follow-Up Doctor Others Which topic do you need to be informed? Epilepsy Migraine Depression Research Device Your E-mail Address Phone Number Patient's diagnosis history (Diagnostic, medications, follow-up doctor...etc.) Submit Thank you for your interest in tVNS Turkey. We will respond to you as soon as possible.

About us The medical technology company Cerbomed GmbH, which was founded in 2003 in Erlangen, led the world in the field of transcutaneous vagus nerve stimulation until 2018. In October 2018, the brand was restructures as tVNS Technologies Gmbh. The new generation device, tVNS®, approved in 2021, is the only non-invasive vagus stimulation device in the world approved for epilepsy, depression, autism, insomnia and many other neurodegenerative diseases. tVNS® has been used in thousands of treatments since 2010 and has significantly improved patients' quality of life. tVNS® devices has been developed and manufactured in Germany. tVNS Health GmbH, based in Munich, Germany is responsible for the worldwide sales and therapy support services for tVNS® devices, serving in more than 40 countries worldwide. Nervovita Medikal Teknolojiler is a medical technology company established by tVNS Health GmbH to carry out its activities in Turkey, Azerbaijan and Balkans, and provides tVNS therapy devices to hundreds of patients. Meet our team Our Vision The patient is at the center of all our activities - customer proximity and customer satisfaction are extremely important to us. Our vision is to increase the quality of life of patients and their loved ones with our solutions, to give them a new life for the future, and to provide a more predictable life. ​ We support our patients in their pursuit of safety, stability, and self-control. İletişim Bilgileri Contact us tvNS Health GmbH ​ Türkiye - Azerbaijan - Northern Cyprus - North Macedonia Office ​ NERVOVITA Medical Technologies ​ RELUX Plaza, FSM Mah Poligon Cad Siir Sok Floor :9 No:58 34771, Umraniye /Istanbul /TURKEY Whatsapp Link +90 850 241 93 15 info@t-vnstherapy.com Our Socia Media Channels tVNS Health GmbH Headqua rter ​ Südliche Münchner Str. 62, 82031 Grünwald, Germany info@tvns.health www.t-vns.com Whatsapp Link +49 89 24410244 info@tvns.health Our Socia Media Channels Contact us Name Surname Your E-mail Address Phone Number Where did you hear about us? Internet search tVNS social media (Facebook, instagram) My Follow-Up Doctor Others Which topic do you need to be informed? Epilepsy Migraine Depression Research Device Patient's diagnosis history (Diagnostic, medications, follow-up doctor...etc.) Submit Thank you for your interest in tVNS Turkey. We will respond to you as soon as possible.

Migraine Symptoms, Causes and Diagnostic Methods Migraine Symptoms Migraine symptoms usually begin in the teenage years. The probability of its occurrence increases from the last stages of adolescence, and this probability decreases after the age of 35. As it is known in people with migraine, the most common and most severe symptom is headache. This headache can sometimes be so severe that it puts the person in bed. The most common areas of migraine attacks are the back of the head, behind the ears and forehead. Other physical symptoms of migraine are the desire to drink excessively, increase in appetite, diarrhea or constipation depending on the situation, and swelling in the abdomen. In addition to these physical symptoms, people who experience migraine attacks also experience various emotional symptoms. Symptoms such as depressed mood, excessive cheerfulness, excessive stagnation, concentration disorders, olfactory sensitivity, attention deficits, hypersensitivity and an intense desire for sleep can be seen. Migraine Causes ​ Migraine is a genetically inherited disease. In other words, migraine is more common in people with a family history of migraine. Although not in the family, women are at risk for migraine headaches during hormonal transition (adolescence, premenstrual days, menopause) and during the periods when they use birth control pills. . The sensory nerve of our face, cerebral vessels and cerebral cortex is the same. This nerve can also be stimulated in external environment triggers and trigger pain mechanisms in the brain. Triggers of Migraine Hormonal changes experienced by women Hormone medications, such as oral contraceptives (birth control pills) and hormone replacement therapy Some foodstuffs Stress plays an important role in migraine attacks. Stress at work or home life may be the cause of frequent migraine attacks. Loud noises, bright lights, or exposure to sunlight Changes in sleep and wake patterns Migraine attacks may occur with sexual activity or intense physical exertion. Ambient air pressure or barometric changes can trigger migraines. Medicines; Vasodilators (vasodilators) such as nitroglycerin or oral contraceptives (birth control pills) can worsen migraines. Brain tumor ​ Migraine Diagnostic Methods ​ Diagnosis is made during the interview by a specialist physician. If you are experiencing any of the following symptoms, you should see a doctor immediately; Sudden, severe headache like thunder Fever, stiff neck, confusion, double vision, drowsiness, or slurred speech Worsening of headache, especially after a head injury A headache that develops after coughing, exertion, straining, or a sudden movement New onset headache over 50, ​ ​ Migraine is not known enough and its treatment is not done because patients do not apply to the neurology department and try to control their headaches with painkillers. If you regularly experience migraine attacks and symptoms, it is useful to record them. If you think that the attacks and severity of your headaches have changed, you should definitely see a neurologist as soon as possible. For the diagnosis of epilepsy, the patient's medical history, frequency and severity of seizures, and symptoms are among the points that physicians pay attention to. Sometimes, extreme stress, fatigue, emotional and hormonal changes can also cause seizures. In this sense, not every seizure indicates epilepsy. Physicians can diagnose after listening to patients' stories. Genetic factors take the first place among the causes of migraine headaches. The incidence of migraine in patients with a family history of migraine varies between 40% and 75%. Hormonal changes also cause an increase in migraine attacks. Migraine attacks are 3 times more common in women than in men. Migraine Who has visible Contact us

tVNS PARKINSON EXPERIENCE Barry Hanner is a famous Baritone opera singer. He has been using the tVNS device for Parkinson's disease for about two years. Before tVNS, he was suffering from disturbance of equilibrium. He uses it four hours a day at least five times a week. He says that the biggest effect of tVNS is eliminating the disturbance of equilibrium. " tVNS was recommended to help me with my Parkinson's disease symptoms. I use it at least 5 times a week. I realized that the tVNS device has eliminated the balance disorder caused by Parkinson's disease.The device's biggest advantage is providing such a recovery without the requirement for any surgical intervention and without being exposed to the side effects of drugs. I have been using tVNS device for over 2 years and will continue to use it." Barry Hanner. We are working for a better life...

The "tVNS Special Issue", has been published in the "Journal Autonomic Neuroscience", the official journal of the International Society for Autonomic Neuroscience, published by Elsevier. We are proud to design the future of neuroscience and to be the pioneer of the medical technologies. Below are the titles of the articles in the journal. Link is below: 1. tVNS in the treatment of drug-resistant epilepsy 2. Cardiovascular responses to low-level transcutaneous vagus nerve stimulation 3. Electrical vagus nerve stimulation as a prophylaxis for SIRS and postoperative ileus 4. tVNS as a potential therapeutic application for neurodegenerative disorders – A focus on dysautonomia in Parkinson's disease 5. tVNS in the management of headache and pain 6. Brain plasticity and vagus nerve stimulation 7. tVNS for the treatment of postural tachycardia syndrome 8. Functional anatomy of the vagus system – Emphasis on the somato-visceral interface 9. Effects of tVNS on cardiovascular autonomic control in health and disease 10. tVNS and heart rate variability: Analysis of parameters and targets 11. Current challenges in reliably targeting the noradrenergic locus coeruleus using transcutaneous auricular vagus nerve stimulation (taVNS) 12. The LC-NE system as a potential target for neuromodulation to ameliorate non-motor symptoms in Parkinson's disease 13. Vagus nerve afferent stimulation: Projection into the brain, reflexive physiological, perceptual, and behavioral responses, and clinical relevance 14. Transcutaneous vagus nerve stimulation (tVNS) in stroke: the evidence, challenges and future directions 15. t-VNS to treat disorders of behaviour in Prader-Willi Syndrome and in people with other neurodevelopmental conditions 16. Technical aspects and future approaches in transcutaneous vagus nerve stimulation (tVNS) 17. A two-week course of transcutaneous vagal nerve stimulation improves global sleep: Findings from a randomised trial in community-dwelling adults https://www.sciencedirect.com/journal/autonomic-neuroscience/special-issue/10DBND1B8HC

tVNS Nemos, that has improved the quality of life , in more than 3000 patients with epilepsy in the world since 2012, was has been applied to the first pediatric resistant epilepsy patient in Turkey last week. tVNS Nemos, which is the size of a mobile phone, stimulates the ear branch of the vagus nerve with the help of a special electrode headset, reduce the frequency and severity of epilepsy seizures by providing vagus nerve stimulation without the need for any invasive intervention and placement of a device in the body as a result of a total of 4 hours of sessions applied every day. As tVNS Turkey, we aim to reach patients who are suitable for tVNS vagus stimulation therapy and to increase the quality of life of our epilepsy patients.