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tVNS Turkiye Team Our team Selin Erdogan Gezen Selin Erdogan Gezen was born in 1980 in Izmir. She graduated from Middle East Technical University, Department of Industrial Engineering in 2002. She started her career at Vestel Electronics. She continued her career as project manager at Arkas Holding and Greencat Rotterdam. She had various positions as business development project manager at Vodafone Turkey, and Internet and Mobile Vice President at Garanti BBVA Bank. She worked as a senior program manager in innovative technology projects in Turkey, United Kingdom and Germany in the enterprise software unit of Hewlett Packard. She started working on neuromodulation technologies as a founding partner of Nervovita Medical Technologies, in 2019. She made transcutaneous vagal nerve stimulation to become an accessible treatment in Turkey. As of January 2022, she is the director of global marketing and operations of Germany-based tVNS® Health Gmbh, and supports clinical studies in different diseases with leading universities and institutes in more than 40 countries around the world. Particularly in pediatric neurology, she played an active role in determining the global protocols of therapy by pioneering successful treatments with her studies with physicians from various countries around the world. Kurtulus Berkay Gezen Berkay Gezen was born in Aydın in 1973. He completed the Department of Electrical and Electronics Engineering at Middle East Technical University in 1995. He took part in various international product development projects for 6 years in product management at Beko Electronics . From 2001 to 2007, he continued to work in international trade activities on consumer electronics. Between 2008 and 2018, he served as the global commercial director of CardiAid, the world's leading automatic defibrillator brand for 11 years, from the design of the brand to its spread in over 65 countries of the world. As of 2019, he provides strategic consultancy services to medical technology start-up companies in Turkey and India with his global experience in his field. He joined the founding team of tVNS Technologies in 2018 as global sales director. As of December 2022, he continues to work as the CEO of Germany-based tVNS Health GmbH, which was established to manage the sales and operations of tVNS® devices all over the world, and continues to invest in medical technology to make vagus neuromodulation treatments accessible all over the world. Senem Erdoğan Atay Senem Erdogan Atay was born in Izmir in 1982. Sh e graduated from Middle East Technical University, Department of Chemical Engineering in 2005. She started her career as North America Operations Officer at Maersk Shipping and continued as Product Manager at Deva İlaç. She worked as Project Engineer at Bekaert, Product Manager of Boston Scientific Pacemakers, and Customer Services Team Manager at Eczacıbaşı Building Products Group. She continued her career as Sales Manager at Enelsan. She joined Nervovita Medical Technologies team as Marketing Manager in 2021 and contributed to making tVNS treatment an accessible and widespread treatment in Turkey. As of July 2022, she continues her career as the manager of tVNS Health GmbH responsible for regulations and clinical studies, and manages global medical approval projects with her India-based clinical team. Oguz Can Ergin After completing his undergraduate education in Biomedical Engineering at Yeditepe University, he completed her master's degree in the same department. Since May 2024, he has been working on medical device technology, neuromodulation clinical research, international and patient device education and support in Türkiye. He speaks English fluently. Eylül Doğa Hallac She completed her associate degree in Audiometry at Şişli University. Since July 2024, she has been working on neuromodulation devices, university and hospital studies, device operations and Türkiye patient device training and support. Ahmed Alsharif He completed his undergraduate education in Ankara University Biomedical Engineering Department. Since June 2024, he has been working in medical device technology, neuromodulation devices, neuromodulation clinical research, international and Turkish patient device education and support. He speaks English and Arabic fluently. Aylin Kesat She completed his undergraduate education in Ankara University Biomedical Engineering Department. Since June 2024, she has been working in medical device technology, neuromodulation devices, neuromodulation clinical research, international and Turkish patient device education and support. She speaks English and Arabic fluently. Mariam Ismaeil She completed his undergraduate education in Ankara University Biomedical Engineering Department. Since June 2024, she has been working in medical device technology, neuromodulation devices, neuromodulation clinical research, international and Turkish patient device education and support. She speaks English and Arabic fluently. Merve Nur Akay She completed his undergraduate education in Ankara University Biomedical Engineering Department. Since June 2024, she has been working in medical device technology, neuromodulation devices, neuromodulation clinical research, international and Turkish patient device education and support. He speaks English and Arabic fluently.

tVNS Transkutanöz Vagus Sinir Stimülasyonu cihazıdır. Dirençli Epilepsi, Migren ve Depresyon Tedavisinde Ameliyatsız İlaçsız Kulaktan Vagus Sinirini Uyaran Dünyanın CE onaylı Tek Nöroterapi - vagus stimulasyonu- cihazıdır. tVNS Türkiye , "t-vnstherapy "tek yetkili satıcısıdır. Changing the World, Changing the Lives In More than 50 Countries of the World With Our 20 Years of Vagus Treatment Experience We Are Here for a Brand New Quality of Life Our tVNS® health solutions help thousands of patients to discover a brand new quality of life. What is tVNS®? tVNS® is a medical device for the treatment of symptoms of sympathovagal imbalance and was specially developed for patients who are not free of symptoms despite drug therapy. tVNS® stimulates the branch of the vagus nerve in the auricle through the skin with gentle electrical impulses. Signals are passed on to the brain via special nerve fibers: first in the brain stem and then in higher centers. The treatment with tVNS® is applied by patients independently. It has been used by thousands of patients and is a treatment with very few side effects. tVNS® is indicated to treat sympathovagal imbalance in the following conditions: Anxiety Migrain Autism Cognitive Impairment Depression Fibromyalgia E p ilepsy Inflammation Pr ader-Willi Syndrome Sleep Disorders Stroke Tinnitus Asthma Crohn's Disease Atrial Fibrillation Parkinson's tVNS® CARE Therapy Tracking THE MOST EFFECTIVE WAY TO GET RESULTS FROM tVNS®* For patient-driven medical device treatments that the patient can apply at home without the supervision of a doctor, the most important need for the success of the treatment is the preparation of a protocol specific to the patient's needs and the remote follow-up by the doctor and an expert team to see whether the patient can use the device correctly. tVNS Care®, o ur unique digital health service, where a patient-specific program is prepared based on the protocols of similar patients in more than 50 countries and all details of the treatment can be followed online by our expert teams. Why Treatment with tVNS® Device? Customized Therapy t VNS® therapies are customized for each patient, based on indication and needs, so can provide a unique solution for every patient. More Flexibility With the help of the rechargeable battery, it allows several different parameters and treatment protocols. Innovative App With the tVNS® Patient App you can track your treatment, share results with your doctor and get therapy consultation wherever you are R emote Training tVNS® allows remote delivery and training without any need for travel, so that any patient can start using the therapy on their home No Surg ery tVNS® enables non-surgical vagus nerve stimulation with full patient control and no invasive- risks Few Side Effects tVNS® has very few side effects compared to drugs and invasive treatments, and easily tolarable. Pediatric Flexibility It can be used safely at any age from newborn babies with the approval of the doctor. Easy to Use tVNS® is easy to use, as small as a smartphone and can be easily integrated into everyday life. Treatment Stories of tVNS® Patients Our doctor Barış Ekici has contributed a lot to my autistic son Kaan. We have benefited greatly from the tVNS treatment, which is Vagus nerve stimulation. We have seen progress in his word count and awareness. He has become calmer, his hyperactivity has decreased, and his sleep has become more regular. Dr. Nurbanu Gürbüzer, Istanbul, Assoc. Prof. Dr. Barış Ekici, mother of a patient followed up Download the tVNS ® Patient App Meet the Tele-Medicine Technologies of the Future With the innovative tVNS® patient app, you can track your treatment at any time and share your data with your doctor. In addition, the tVNS® patient app enables us to continuously improve our technology and optimize your treatment. The tVNS® Patient App is available now in the Google Play Store and in the Apple App Store (EU-only). How does tVNS® work? You can use tVNS® anytime, anywhere. It is easy to use, portable and discrete. tVNS® activates special nerve fibers through gentle electrical impulses (neurostimulation) via an ear electrode on the ear, stimulating the branch of the vagus nerve in the auricle through the skin, by sending nerve signals to the brainstem and the higher centers. This alleviates symptoms of sympathovagal imbalance, for example reducing seizures in epilepsy. Watch this short video to learn more about our tVNS® health solutions and how tVNS® works. blog Contact us Name Surname Where did you hear about us? * Internet search tVNS social media (Facebook, instagram) My Follow-Up Doctor Others Which topic do you need to be informed? * Epilepsy Migraine Depression Research Device Your E-mail Address Phone Number Patient's diagnosis history (Diagnostic, medications, follow-up doctor...etc.) Submit Thank you for your interest in tVNS Turkey. We will respond to you as soon as possible. Contact us

tVNS E - İlaca Dirençli Epilepsi için Ameliyatsız Tedavi. İlacın yeterli olmadığı durumlarda vagus sinir stimulasyonu tVNS E, dirençli epilepsi ve major depresyon tedavisinde kullanılan dünyanın tek onaylı non-invazif vagus terapi cihazıdır INSOMNIA (SLEEP DISORDER) Groundbreaking Technologies for Life What is Insomnia? Insomnia is a common sleep disorder that makes it difficult to fall asleep and stay asleep, or to wake up too early and not be able to go back to sleep. People with insomnia feel tired when they wake up. Insomnia can reduce not only energy level and mood, but also health, work performance and quality of life. It is the disease of not being able to sleep in sufficient time and restful sleep. During the existence of the disease, symptoms such as irregularity in sleeping hours, sudden night awakenings, difficulty falling asleep after waking up, and waking up very early in the morning are observed. The existence of a regular sleep time and long naps does not mean that we will wake up the next day rested and ready to work. In studies on sleep and sleeping problems, it is said that an adult individual should sleep 7-8 hours every night. However, the resting process, which d iffers from person to person, can change the person's sleep duration. Tinnitus and Vagus Nerve Stimulation Tinnitus can also be defined as the patient's perception of a sound without an acoustic stimulus. This sound can have different tones, features and characters. The sound most often heard as ringing is sometimes described as humming, bells, wind or whistling, machinery noise, rustling, pulsing sounds. Tinnitus is considered as a symptom rather than a disease and is treated as such. It is the most common symptom of the auditory system. These complaints may be severe enough to cause mental problems or severely impair the quality of life, and in some people, tinnitus may come and go within a few minutes. Clinical studies have shown that vagus nerve stimulation provides an increase in parasympathetic activity, calms the patient, reduces sleep disorders due to tinnitus, and decreases THI (Tinnitus Handicap Inventoy). For more detailed information, please contact tVNS Turkey. Tinnitus and Vagus Nerve Stimulation Tinnitus can also be defined as the patient's perception of a sound without an acoustic stimulus. This sound can have different tones, features and characters. The sound most often heard as ringing is sometimes described as humming, bells, wind or whistling, machinery noise, rustling, pulsing sounds. Tinnitus is considered as a symptom rather than a disease and is treated as such. It is the most common symptom of the auditory system. These complaints may be severe enough to cause mental problems or severely impair the quality of life, and in some people, tinnitus may come and go within a few minutes. Clinical studies have shown that vagus nerve stimulation provides an increase in parasympathetic activity, calms the patient, reduces sleep disorders due to tinnitus, and decreases THI (Tinnitus Handicap Inventoy). For more detailed information, please contact tVNS Turkey. Tinnitus and Vagus Nerve Stimulation Is tVNS® treatment painful? No. The tVNS® device delivers mild electrical impulses through the ear. Patients typically feel this as a tingling or gentle vibration. Do I need to use the device every day? Yes, regular use is important for optimal treatment results. The duration and frequency of application are determined by factors such as the patient's age and indication. Are there any side effects? Side effects of tVNS® treatment are generally mild. A rare side effect is mild skin irritation at the application site. How long does it take to see results? Some patients experience positive changes in sleep and mood within the first weeks, while reductions in tinnitus intensity may be noticeable within a few weeks to months. Tinnitus and Vagus Nerve Stimulation Individuals whose sleep and quality of life are impaired due to tinnitus Those seeking treatment without medication or surgery Patients with high psychological impact (anxiety, restlessness) Users who prefer a minimally invasive and safe method Contact us Contact us

tVNS PARKINSON EXPERIENCE Barry Hanner is a famous Baritone opera singer. He has been using the tVNS device for Parkinson's disease for about two years. Before tVNS, he was suffering from disturbance of equilibrium. He uses it four hours a day at least five times a week. He says that the biggest effect of tVNS is eliminating the disturbance of equilibrium. " tVNS was recommended to help me with my Parkinson's disease symptoms. I use it at least 5 times a week. I realized that the tVNS device has eliminated the balance disorder caused by Parkinson's disease.The device's biggest advantage is providing such a recovery without the requirement for any surgical intervention and without being exposed to the side effects of drugs. I have been using tVNS device for over 2 years and will continue to use it." Barry Hanner. We are working for a better life...

The "tVNS Special Issue", has been published in the "Journal Autonomic Neuroscience", the official journal of the International Society for Autonomic Neuroscience, published by Elsevier. We are proud to design the future of neuroscience and to be the pioneer of the medical technologies. Below are the titles of the articles in the journal. Link is below: 1. tVNS in the treatment of drug-resistant epilepsy 2. Cardiovascular responses to low-level transcutaneous vagus nerve stimulation 3. Electrical vagus nerve stimulation as a prophylaxis for SIRS and postoperative ileus 4. tVNS as a potential therapeutic application for neurodegenerative disorders – A focus on dysautonomia in Parkinson's disease 5. tVNS in the management of headache and pain 6. Brain plasticity and vagus nerve stimulation 7. tVNS for the treatment of postural tachycardia syndrome 8. Functional anatomy of the vagus system – Emphasis on the somato-visceral interface 9. Effects of tVNS on cardiovascular autonomic control in health and disease 10. tVNS and heart rate variability: Analysis of parameters and targets 11. Current challenges in reliably targeting the noradrenergic locus coeruleus using transcutaneous auricular vagus nerve stimulation (taVNS) 12. The LC-NE system as a potential target for neuromodulation to ameliorate non-motor symptoms in Parkinson's disease 13. Vagus nerve afferent stimulation: Projection into the brain, reflexive physiological, perceptual, and behavioral responses, and clinical relevance 14. Transcutaneous vagus nerve stimulation (tVNS) in stroke: the evidence, challenges and future directions 15. t-VNS to treat disorders of behaviour in Prader-Willi Syndrome and in people with other neurodevelopmental conditions 16. Technical aspects and future approaches in transcutaneous vagus nerve stimulation (tVNS) 17. A two-week course of transcutaneous vagal nerve stimulation improves global sleep: Findings from a randomised trial in community-dwelling adults https://www.sciencedirect.com/journal/autonomic-neuroscience/special-issue/10DBND1B8HC

tVNS Nemos, that has improved the quality of life , in more than 3000 patients with epilepsy in the world since 2012, was has been applied to the first pediatric resistant epilepsy patient in Turkey last week. tVNS Nemos, which is the size of a mobile phone, stimulates the ear branch of the vagus nerve with the help of a special electrode headset, reduce the frequency and severity of epilepsy seizures by providing vagus nerve stimulation without the need for any invasive intervention and placement of a device in the body as a result of a total of 4 hours of sessions applied every day. As tVNS Turkey, we aim to reach patients who are suitable for tVNS vagus stimulation therapy and to increase the quality of life of our epilepsy patients.