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tVNS® Therapy Devices Treatments of the Future, From Today tVNS Therapy Devices tVNS® vagus therapy devices offer a non-surgical neuromodulation treatment option by providing auricular vagus nerve stimulation in difficult-to-treat brain diseases with the help of a smartphone-sized device and a special electrode. With its innovative mobile application, the patient can share all the treatment information with a single click without leaving his home, and reach the necessary follow-up and support. tVNS® stimulates the branch of the vagus nerve in the auricle through the skin with gentle electrical impulses. Signals are passed on to the brain via special nerve fibers: first in the brain stem and then in higher centers. The treatment with tVNS® is applied by patients independently. It has been used by thousands of patients and is a treatment with very few side effects. tVNS Health website tVNS® is approved for the treatment of the following indications. ✓Anxiety ✓Atrial Fibrillation ✓Autism ✓Cognitive Impairment ✓Epilepsy ✓Crohn's Disease ✓Migraine ✓Parkinson's Disease ✓Depression ✓Prader-Willi Syndrome ✓Sleep Disorder ✓Systemic Sclerosis ✓Tinnitus Why Treatment with tVNS® Device? Minimal Side Effects Transitioning away from traditional medications often comes with the pursuit of fewer side effects. tVNS®, being drug-free, ensures a therapeutic experience with reduced potential for long-term adverse outcomes, positioning itself as a safer alternative. EU-MDR Approved Medical Device EU-MDR Cla ss IIa tVNS® is the only non-invasive vagus nerve stimulation (VNS) device approved under the European Medical Device Regulation (EU-MDR). Our device features a unique stimulation technology targeting the concha cymba, providing 100% innervation of the auricular branch of the vagus nerve. Unlike other devices on the market, they provide partial innervation by stimulating different anatomical regions and are not manufactured to the same quality and safety standards as tVNS®. Clinical Approach That Does Not Require Surgery tVNS® provides the clinical effectiveness of vagus nerve stimulation without the risks and operational difficulties associated with surgery. This allows patients to experience significant therapeutic benefits in a non-invasive manner, under their own control. Low Side Effects Various treatment methods are used to minimize medication side effects. tVNS®, which does not require medication, reduces the risk of long-term adverse effects and offers a safer treatment option. German Engineering Our commitment to excellence ensures that every device meets the highest standards of quality and performance. tVNS® is built on durability and innovative design, reflecting the renowned precision of German engineering and manufacturing. It is trusted by healthcare professionals and researchers worldwide. Groundbreaking Technology Tracking and understanding your treatment progress is crucial. Our specially developed tVNS® Patient App not only provides real-time monitoring but also allows you to easily share your data with your healthcare professionals. Easy Access from Anywhere Today, the convenience of remote access has become essential. tVNS® takes this convenience a step further, delivering your device directly to your address and offering distance learning opportunities. You can begin your treatment immediately, without travel or time constraints. Pediatric Flexibility Approved for pediatric use, it can be used from newborn onwards with doctor's approval as it is not an invasive intervention. Easy to Use tVNS® is easy to use, as small as a smartphone and easily integrated into everyday life. How does tVNS ® work? With tVNS® ①, light electrical stimulation ④ is given to the vagus nerve ② in the ear ③. These signals are special nerve fibers in the brain stem ⑤ before and then transmitted to the brain via the respective control centers. These stimuli cause the release of neurotransmitters from the brain and increase parasympathetic activity. Treatment with tVNS® is applied by the patient himself. It can be easily integrated into daily life. How does tVNS ® work? With tVNS® ①, light electrical stimulation ④ is given to the vagus nerve ② in the ear ③. These signals are special nerve fibers in the brain stem ⑤ before and then transmitted to the brain via the respective control centers. These stimuli cause the release of neurotransmitters from the brain and increase parasympathetic activity. Treatment with tVNS® is applied by the patient himself. It can be easily integrated into daily life. More Information tVNS® CARE Therapy Tracking tVNS® CARE Therapy Tracking In medical device treatments that can be applied at home without a doctor's supervision, the most important requirement for the success of the treatment is that a protocol specific to the patient's needs is prepared and that the patient is using the device correctly and is monitored by the doctor and a team of experts. The world-unique tVNS Care® Technology is a digital health service that can increase the success rate of treatment by up to 50%*, where a patient-specific program is prepared by referencing the protocols of similar patients in more than 50 countries, and all details of the treatment can be monitored online by our expert teams. tVNS® Assurance The tVNS® Promise We offer you a clinically proven medical device that has shown its effectiveness in scientific studies and helps over 2,000 patients to go about their everyday lives without to overcome l imitations. We promise you a high-quality treatment device that has been tested by our quality system. We are there for you. Our customer advisors can be reached via our service portal and by e-mail as competent contacts.

tVNS E - İlaca Dirençli Epilepsi için Ameliyatsız Tedavi. İlacın yeterli olmadığı durumlarda vagus sinir stimulasyonu tVNS E, dirençli epilepsi ve major depresyon tedavisinde kullanılan dünyanın tek onaylı non-invazif vagus terapi cihazıdır AUTISM Symptoms, Causes and Diagnostic Methods Autism Symptoms Lack of social communication Can't make eye contact They do not react to what is said lack of speech They do not feel danger and fear They don't look back when their name is called They tend to walk on their toes. Sensitivity to light and sound Causes of Autism Although the exact cause of autism has not been found, it is stated by experts as a genetic disease. Psychological problems experienced by the mother before birth, gene mutation, alcohol and cigarette use increase the risk of the baby having autism. Autism Diagnostic Methods Early diagnosis is very important in autism symptoms that show limited and repetitive behaviors. It is necessary to get help by monitoring the child's behavior by a specialist physician. Autism diagnosed at the age of 2 to 4 years has high reliability levels. Who Has Autism visible Autism is more common in boys than girls. Approximately 3.6% of boys and 1.3% of girls between the ages of 3 and 17 have autism spectrum. According to the data released by the World Health Organization in 2021, one out of every 160 children in the world is diagnosed with autism. Contact us

Transkutanöz Vagus Sinir Stimülasyonu (tVNS), vagus sinirine bir kulakluk yardımıyla elektriksel uyarılar verilmesini içeren tıbbi bir tedavidir . Dirençli epilepsi, kronik migren ve ilaca dirençli depresyon için etkili bir tedavi olarak kullanılır. What is Vagus Nerve? Discover The vagus nerve is the longest cranial nerve in the body. It comes from the Latin word, vagus, for “wandering.” That’s because it wanders throughout your body, with wide distribution connecting the brainstem to the body. Only mammals have this nerve. The vagus nerve serves as the body's superhighway, carrying information between the brain and the internal organs and controlling the body's response in times of rest and relaxation. It helps the immune system and inflammation response to disease. It has four main functions: sensory, special sensory, motor and parasympathetic. The vagus nerve also manages fears and sends information from the gut to the brain, which is linked to dealing with stress, anxiety, and fear–hence the saying, ‘gut feeling'. Historical Development of Vagus Nerve Stimulation Epilepsy has existed in human history with the first record found in a Babylonian text written 4000 years ago, and humanity has sought a cure for this disease for centuries. With the emergence of neurology in the 19th century, the mechanism between the nervous system and epilepsy was tried to be solved and the first vagus nerve stimulation was tried by a New York neurologist in the early 1880s. Over the next 100 years, the effects of vagus nerve stimulation were first investigated in animal experiments, then in humans, and in 1996, the vagus nerve was surgically implanted into the body and become an invasive stimulation option. At the beginning of the 2000s, for eliminating the side effects of invasive VNS, scientists tried to find out ways to stimulate the vagus nerve non-invasively, and by 2010 these studies were concluded successfully. Our first generation device, Nemos, was approved in 2010 for the treatment of epilepsy and depression, and Vitos in 2012 for the treatment of pain and migraine, as the first medically approved non-invasive vagus nerve stimulation treatment in the world. Our 2nd generation device, tVNS-L, has been approved in 2021, and has become a treatment option used in many neurodegenerative diseases. Vagus Nerve Stimulation Effect Overview Regulation of neurotransmitter release Increase in parasympathetic activity Increase in brain neuroplasticity Reducing inflammation Increasing the secretion of serotonin and increasing the mood What Are the Effects of Vagus Nerve Stimulation? Stimulation of the vagus triggers regulatory mechanisms in the nervous, immune, autonomic, endocrine, cardiorespiratory, and gastrointestinal systems. Clinical studies on the vagus nerve have shown that the activity in this nerve is closely related to epilepsy, depression, migraine, headache, inflammatory bowel disease, Alzheimer's, arthritis and many other common disorders by activating the parasympathetic nervous system in the brain and increasing the secretion of neurotransmitters in special regions of the brain. shows. Vagus nerve stimulation therapies are approved by FDA in the USA and CE in Europe for use in treatments such as mood improvement, pain relief, sleep improvement, memory enhancement and anxiety reduction. Research continues on the effects of neuroplasticity as well as its cardiac and inflammatory properties. Contact us

PATIENT DECLARATION FORM CLINICAL DIAGNOSIS & HEALTH CONDITIONS

Vagus nerve stimulation for depression DEPRESSION Groundbreaking Technologies for Life What is Depression? Depression is a mood disorder that causes constant sadness and loss of interest. Depression is also called major depressive disorder or clinical depression. The feelings, thoughts and behaviors of individuals suffering from this condition are affected and various emotional or physical problems may arise due to this. There may be problems doing normal daily activities, and sometimes life may seem not worth living. Depression is not just a feeling of malaise or momentary weakness. Depression is also not such a simple problem that it can be solved in an instant. Depression is a treatable medical condition that requires treatment. This treatment process may take a long time in some cases. Everyone goes through periods of not feeling well emotionally and psychologically from time to time. These periods generally last for a certain period of time, depending on the intensity of the troubles and sorrows you experience. However, if your bad periods last longer than two or three weeks and prevent you from doing many of the things you do in your daily life properly; this condition is called depression (major depressive disorder). Targeted Benefits in the Treatment of Depression with tVNS® Migraine is a genetically inherited disease. In other words, migraine is more common in people with a family history of migraine. Although not in the family, women are at risk for migraine headaches during hormonal transition (adolescence, premenstrual days, menopause) and during the periods when they use birth control pills. . The sensory nerve of our face, cerebral vessels and cerebral cortex is the same. This nerve can also be stimulated in external environment triggers and trigger pain mechanisms in the brain. During migraine, the cerebral vessels first narrow and then expand. The increase in pressure due to enlargement in the brain vessels is the cause of the throbbing finding in the person. Migraine is a genetically inherited disease. In other words, migraine is more common in people with a family history of migraine. Although not in the family, women are at risk for migraine headaches during hormonal transition (adolescence, premenstrual days, menopause) and during the periods when they use birth control pills. . The sensory nerve of our face, cerebral vessels and cerebral cortex is the same. This nerve can also be stimulated in external environment triggers and trigger pain mechanisms in the brain. During migraine, the cerebral vessels first narrow and then expand. The increase in pressure due to enlargement in the brain vessels is the cause of the throbbing finding in the person. Why Are Alternative Treatment Options Needed? Migraine is a genetically inherited disease. In other words, migraine is more common in people with a family history of migraine. Although not in the family, women are at risk for migraine headaches during hormonal transition (adolescence, premenstrual days, menopause) and during the periods when they use birth control pills. . The sensory nerve of our face, cerebral vessels and cerebral cortex is the same. This nerve can also be stimulated in external environment triggers and trigger pain mechanisms in the brain. During migraine, the cerebral vessels first narrow and then expand. The increase in pressure due to enlargement in the brain vessels is the cause of the throbbing finding in the person. Meet tVNS®: A New Approach to Depression Through the Vagus Nerve Migraine is a genetically inherited disease. In other words, migraine is more common in people with a family history of migraine. Although not in the family, women are at risk for migraine headaches during hormonal transition (adolescence, premenstrual days, menopause) and during the periods when they use birth control pills. . The sensory nerve of our face, cerebral vessels and cerebral cortex is the same. This nerve can also be stimulated in external environment triggers and trigger pain mechanisms in the brain. During migraine, the cerebral vessels first narrow and then expand. The increase in pressure due to enlargement in the brain vessels is the cause of the throbbing finding in the person. " The scientific solution for depression: tVNS®. The life of a 17-year-old girl diagnosed with medication-resistant, suicidal depression was completely changed by transcutaneous vagus nerve stimulation. This clinically proven, non-invasive method is especially promising for young individuals. It enables the safe management of depression by affecting the brain's mood centers via the vagus nerve. Key Features of tVNS®: Clinically proven effectiveness, non-invasive and drug-free therapy, the ability to monitor your recovery process, and suitability for pediatric use. " Who is it suitable for? tVNS® can be a complementary solution in the following situations: Individuals experiencing mild, moderate and severe depression Those who do not benefit sufficiently from drug treatment Those seeking alternatives due to drug side effects Those who experience depression along with anxiety and sleep disturbances What is Depression? What is Depression? Depression is a mood disorder that causes constant sadness and loss of interest. Depression is also called major depressive disorder or clinical depression. The feelings, thoughts and behaviors of individuals suffering from this condition are affected and various emotional or physical problems may arise due to this. There may be problems doing normal daily activities, and sometimes life may seem not worth living. Depression is not just a feeling of malaise or momentary weakness. Depression is also not such a simple problem that it can be solved in an instant. Depression is a treatable medical condition that requires treatment. This treatment process may take a long time in some cases. Everyone goes through periods of not feeling well emotionally and psychologically from time to time. These periods generally last for a certain period of time, depending on the intensity of the troubles and sorrows you experience. However, if your bad periods last longer than two or three weeks and prevent you from doing many of the things you do in your daily life properly; this condition is called depression (major depressive disorder). Adolescence is a critical period when depression most frequently begins and treatment-resistant cases are observed. Safe and non-invasive options are needed for adolescents who fail to respond to traditional treatments. Transcutaneous auricular vagus nerve stimulation (taVNS) is a new method that can be applied without the need for surgery by stimulating the vagus nerve through the ear. In this study, a 17-year-old girl with treatment-resistant depression received taVNS treatment for 7.5 months, with daily sessions at home, in conjunction with escitalopram therapy, and under regular monitoring by the clinical team. A total of over 270 sessions were administered, with an average daily use of approximately 3 hours. Aside from mild skin irritation, no serious side effects were observed, and cardiac safety tests were normal. Depression severity decreased during treatment, both as assessed by self-report and clinician assessments. The patient completed high school and entered university, and partial improvements in functioning were noted. The results suggest that taVNS is a feasible, safe, and promising complementary treatment option for adolescents. Minimal Side effect The device is applied through the ear, does not require surgery and has minimal side effects. Possibility of Application at Home It can be easily used by the patient on a daily basis in his or her own home environment. Approved and Safe Approved as a Class IIa medical device under the European Union MDR 2017/745 Complementary to Drug Therapy It can be used alongside drug therapy; there is no need to interrupt treatment. Personalized Therapy Stimulation parameters can be adjusted individually to the patient. Types of Depression Symptoms Types of Depression The symptoms caused by major depression are different for each individual. Medical professionals look for various markers or traits that clarify an individual's type of depression. A marker or feature may indicate the presence of a particular type of depression: Anxiety distress : Unusual restlessness or depression with worry about possible events or loss of control. Atypical features : Depression with temporary happiness from certain events, increased appetite, excessive need for sleep, hypersensitivity to rejection, and a feeling of heaviness in the organs. WE DESIGN THE MEDICAL TECHNOLOGIES OF THE FUTURE Contact us Contact us

tVNS E - İlaca Dirençli Epilepsi için Ameliyatsız Tedavi. İlacın yeterli olmadığı durumlarda vagus sinir stimulasyonu tVNS E, dirençli epilepsi ve major depresyon tedavisinde kullanılan dünyanın tek onaylı non-invazif vagus terapi cihazıdır Epilepsy Symptoms, Causes and Diagnostic Methods Epilepsy Symptoms Since epilepsy is a dysfunction that occurs in the brain, the symptoms of epilepsy may vary depending on the function of the affected area of the brain. We can list some symptoms of the disease as follows: Sudden contractions in the body Loss of consciousness Very rapid nodding Uncontrollable shaking in arms and legs wink quickly Looking at a fixed point Being unable to react to sounds or speech for a short time Fear, anxiety or deja vu etc. psychological symptoms Epilepsy Causes Epilepsy is a condition that can have many causes and can occur at any age. It usually starts in childhood. Any disease that affects the brain can cause epileptic seizures. Infections in the womb Birth traumas, lack of oxygen during birth Head injury Genetic and metabolic diseases High fever diseases, Excessive low blood sugar, Intracranial tumors, Brain inflammations. Paralysis Brain tumor Developmental brain malformations Brain infections such as meningitis can lead to epilepsy, Vascular abnormalities, especially in the brain vessels of individuals in the advanced age group, Some epilepsies occur as a result of an electrical activity spreading from this region as a result of disruption in a certain region of the brain. Epilepsies resulting from brain tumors and traumas can be given as examples for this situation. In some types of epilepsy, there is no damage in a single area. An epileptic seizure begins suddenly in the entire brain. Childhood-onset epilepsies are usually of this type. Types of epilepsy also differ from person to person, and this situation also affects the causes and causes of epilepsy. Because not every epilepsy person shows the same symptoms. Epilepsy Diagnostic Methods Imaging methods are one of the primary methods used in the diagnosis of epilepsy. (EEG), (MR) and computed tomography are among the most commonly used imaging methods. EEG, which indicates the electrical activity of the brain, is especially important in the diagnosis of epilepsy. Thanks to EEG, regions of the brain with uncontrolled bioelectrical activity are detected. Whether there is any structural problem that causes seizures is understood by MRI and tomography. If required by specialist physicians, blood and urine tests are also performed. For the diagnosis of epilepsy, the patient's medical history, frequency and severity of seizures, and symptoms are among the points that physicians pay attention to. Sometimes, extreme stress, fatigue, emotional and hormonal changes can also cause seizures. In this sense, not every seizure indicates epilepsy. Physicians can diagnose after listening to patients' stories. People with epilepsy About 50 million people in the world have epilepsy, making epilepsy one of the most common neurological diseases worldwide. It can be seen at any age, although it is more common in childhood and over 65 years of age. Epilepsy can occur in both sexes at any age and in any geographic area. Most people are likely to have an epileptic seizure once in their lifetime. People with more than one epileptic seizure are considered epileptic and should be treated with appropriate medications. In Turkey, 7 out of every 1000 people suffer from epilepsy. Contact us

tVNS E - İlaca Dirençli Epilepsi için Ameliyatsız Tedavi. İlacın yeterli olmadığı durumlarda vagus sinir stimulasyonu tVNS E, dirençli epilepsi ve major depresyon tedavisinde kullanılan dünyanın tek onaylı non-invazif vagus terapi cihazıdır EPILEPSY Breakthrough Technologies for Life What is Epilepsy? Epileptic seizure (or seizure) is a clinical condition that occurs when the normal activity of the brain is disrupted as a result of temporary abnormal electrical activity in nerve cells. Epilepsy, also known as "Sara Disease" among the people, manifests itself with epileptic seizures. Epilepsy is a chronic disease. It develops in people who have brain damage during or after birth for any reason. It is a disease seen in 1% of the population in the world and in our country, and about 70% of these patients can be treated with epilepsy drugs called antiepileptic. More than 30 percent of all epileptic patients continue to have seizures despite taking appropriate medications (anticonvulsants) for epileptic seizures, a condition called refractory epilepsy. Several treatment options are available for patients in this condition. SYMPTOMS Read more REASONS Read more WHO IS SEEN IN Read more DIAGNOSTIC METHODS Read more Types of Epilepsy Doctors have described more than 30 different types of seizures, ranging from very brief shifts of attention to prolonged seizures. The frequency of seizures is also variable, with some patients having less than one seizure per year, while others may experience multiple seizures per day. Seizures are generally divided into two main groups (partial or generalized seizures) depending on the area of abnormal electrical activity in the brain. Partial Seizures: Partial seizures begin and affect only one part of the brain. Also known as 'focal', these seizures can be seen in the following ways. Secondary Generalized: A seizure that begins as a partial seizure and spreads to the rest of the brain, becoming a generalized seizure. Complex: The person experiences changes in consciousness and loss of consciousness, which causes confusion. The person may experience a dreamlike state or exhibit strange and repetitive behaviors such as emotional outbursts or blinks and tics. Generalized Seizures: Generalized seizures occur as a result of abnormal activity in both halves of the brain simultaneously. Absence Seizures: Associated with a shift of consciousness in which the person seems to be immersed in the void. This condition usually begins in childhood and is confused with attention deficit. Simple seizures: Despite seizure activity, the person is conscious and remains aware of those around them. An abnormal twitching, lethargy, sweating, drowsiness, nausea, disturbances of perception and memory, and a feeling of 'deja vu' may occur. Treatment Options for Drug-Resistant Epilepsy Epilepsy Surgery It is the surgical intervention of areas of the brain that cause epileptic seizures and do not perform their normal functions. More information Invasive Vagus Nerve Stimulation (iVNS) A pacemaker is surgically implanted under the chest and an electrode is placed in the vagus nerve in the neck. The electrodes stimulate the vagus nerve near the carotid artery at regular intervals. More information Antiepileptic Drugs They are designed to correct the chemical imbalance in brain cells that causes seizures. These medications work in different ways, some of which are not yet fully understood. More information Transcutaneous Vagus Nerve Stimulation (tVNS) It is a treatment option that stimulates the centers in the brain by stimulating the vagus nerve with the help of an electrode attached to the ear. More information WE DESIGN THE MEDICAL TECHNOLOGIES OF THE FUTURE Contact us

2012 yılından bu yana epilepsi, migren ve depresyona karşı etkinliğini test edebilmek için, transkutanöz vagus siniri uyarımı, tVNS E ve tVNS M üzerine dünyanın çeşitli üniversite ve araştırma klinklerinde çok sayıda çalışma ve araştırmalar yapılmıştır. Science for a better life We Design the Treatments of the Future Clinical Studies Vagus nerve stimulation (VNS) has become a standard therapeutic option for patients with treatment resistant epilepsy and depression and globally is gaining increasing acceptance. Based on the positive experiences with implantable systems, transcutaneous vagus nerve stimulation (tVNS) was first introduced 20 years ago. The field of tVNS is rapidly expanding since the external stimulation is non-invasive and thus avoids numerous side-effects of invasive VNS; tVNS is easily accessible, less expensive and therefore more readily available than conventional VNS. However, transcutaneous stimulation of the outer ear poses new questions regarding the optimal stimulation site and stimulus parameters as well as the physiology and pathways of transcutaneous auricular VNS. Moreover, therapeutic options and realistically reachable goals of tVNS need to be explored. During the last 20 years, basic and clinical research has unraveled many of these questions and augmented our understanding of tVNS pathways and physiologic effects. The number of publications increased exponentially within the last three years and continues to grow rapidly. Many questions have been addressed and therapeutic indications beyond the treatment of drug-resistant epilepsy and depression are steadily expanding and continue to be explored. Redgrave 2018: Safety and Tolerability of tvNS Wrede Case Study 2019 : Sustained seizure freedom with transcutaneous vagal nerve stimulation in drug-resistant epilepsy caused by subcortical band heterotopias Yakunina 2016: Optimization of Transcutaneous Vagus Nerve Stimulation Using Functional MRI Ellrich 2019: Transcutaneous Auricular Vagus Nerve Stimulation Study Bauer 2015: Transcutaneous Vagus Nerve Stimulation (tVNS) for Treatment of Drug-Resistant Epilepsy: A Randomized, Double-Blind Clinical Trial Straube 2015: Treatment of chronic migraine with Transcutaneous stimulation of the auricular branch of the vagal nerve (auricular t-VNS): a randomized, monocentric clinical trial tVNS JOURNAL The "tVNS Special Issue", which includes 17 studies on our tVNS devices, has been published in the "Journal Autonomic Neuroscience" by Elsevier, the official journal of the International Society for Autonomic Neuroscience. Journal Please contact us if you would like to receive more information about the results of many clinical studies and ongoing studies, apart from the studies given as examples above. Contact us

tVNS Transkutanöz Vagus Sinir Stimülasyonu cihazıdır. Dirençli Epilepsi, Migren ve Depresyon Tedavisinde Ameliyatsız İlaçsız Kulaktan Vagus Sinirini Uyaran Dünyanın CE onaylı Tek Nöroterapi - vagus stimulasyonu- cihazıdır. tVNS Türkiye , "t-vnstherapy "tek yetkili satıcısıdır. Changing the World, Changing the Lives In More than 50 Countries of the World With Our 20 Years of Vagus Treatment Experience We Are Here for a Brand New Quality of Life Our tVNS® health solutions help thousands of patients to discover a brand new quality of life. What is tVNS®? tVNS® is a medical device for the treatment of symptoms of sympathovagal imbalance and was specially developed for patients who are not free of symptoms despite drug therapy. tVNS® stimulates the branch of the vagus nerve in the auricle through the skin with gentle electrical impulses. Signals are passed on to the brain via special nerve fibers: first in the brain stem and then in higher centers. The treatment with tVNS® is applied by patients independently. It has been used by thousands of patients and is a treatment with very few side effects. tVNS® is indicated to treat sympathovagal imbalance in the following conditions: Anxiety Migrain Autism Cognitive Impairment Depression Fibromyalgia E p ilepsy Inflammation Pr ader-Willi Syndrome Sleep Disorders Stroke Tinnitus Asthma Crohn's Disease Atrial Fibrillation Parkinson's tVNS® CARE Therapy Tracking THE MOST EFFECTIVE WAY TO GET RESULTS FROM tVNS®* For patient-driven medical device treatments that the patient can apply at home without the supervision of a doctor, the most important need for the success of the treatment is the preparation of a protocol specific to the patient's needs and the remote follow-up by the doctor and an expert team to see whether the patient can use the device correctly. tVNS Care®, o ur unique digital health service, where a patient-specific program is prepared based on the protocols of similar patients in more than 50 countries and all details of the treatment can be followed online by our expert teams. Why Treatment with tVNS® Device? Customized Therapy t VNS® therapies are customized for each patient, based on indication and needs, so can provide a unique solution for every patient. More Flexibility With the help of the rechargeable battery, it allows several different parameters and treatment protocols. Innovative App With the tVNS® Patient App you can track your treatment, share results with your doctor and get therapy consultation wherever you are R emote Training tVNS® allows remote delivery and training without any need for travel, so that any patient can start using the therapy on their home No Surg ery tVNS® enables non-surgical vagus nerve stimulation with full patient control and no invasive- risks Few Side Effects tVNS® has very few side effects compared to drugs and invasive treatments, and easily tolarable. Pediatric Flexibility It can be used safely at any age from newborn babies with the approval of the doctor. Easy to Use tVNS® is easy to use, as small as a smartphone and can be easily integrated into everyday life. Treatment Stories of tVNS® Patients Our doctor Barış Ekici has contributed a lot to my autistic son Kaan. We have benefited greatly from the tVNS treatment, which is Vagus nerve stimulation. We have seen progress in his word count and awareness. He has become calmer, his hyperactivity has decreased, and his sleep has become more regular. Dr. Nurbanu Gürbüzer, Istanbul, Assoc. Prof. Dr. Barış Ekici, mother of a patient followed up Download the tVNS ® Patient App Meet the Tele-Medicine Technologies of the Future With the innovative tVNS® patient app, you can track your treatment at any time and share your data with your doctor. In addition, the tVNS® patient app enables us to continuously improve our technology and optimize your treatment. The tVNS® Patient App is available now in the Google Play Store and in the Apple App Store (EU-only). How does tVNS® work? You can use tVNS® anytime, anywhere. It is easy to use, portable and discrete. tVNS® activates special nerve fibers through gentle electrical impulses (neurostimulation) via an ear electrode on the ear, stimulating the branch of the vagus nerve in the auricle through the skin, by sending nerve signals to the brainstem and the higher centers. This alleviates symptoms of sympathovagal imbalance, for example reducing seizures in epilepsy. Watch this short video to learn more about our tVNS® health solutions and how tVNS® works. blog Contact us Name Surname Where did you hear about us? * Internet search tVNS social media (Facebook, instagram) My Follow-Up Doctor Others Which topic do you need to be informed? * Epilepsy Migraine Depression Research Device Your E-mail Address Phone Number Patient's diagnosis history (Diagnostic, medications, follow-up doctor...etc.) Submit Thank you for your interest in tVNS Turkey. We will respond to you as soon as possible. Contact us