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tVNS E - İlaca Dirençli Epilepsi için Ameliyatsız Tedavi. İlacın yeterli olmadığı durumlarda vagus sinir stimulasyonu tVNS E, dirençli epilepsi ve major depresyon tedavisinde kullanılan dünyanın tek onaylı non-invazif vagus terapi cihazıdır Crohn's Disease Groundbreaking Technologies for Life What is Crohn's Disease ? Crohn's disease is a type of inflammatory bowel disease that causes inflammation of the gastrointestinal tract from the mouth to the anus. This inflammation can be attached to one or more parts of the digestive system, but it is usually seen in the ileum, which is the last part of the small intestine, and in the beginning of the large intestine. Crohn's disease can cause inflammation in your digestive tract, leading to abdominal pain, severe diarrhea, fatigue, weight loss, and malnutrition. Growth-development retardation in children may be signs of Crohn's disease. Extra-intestinal diseases are also observed in a quarter of Crohn's patients. These mostly occur in the skin, joints, eyes, liver and biliary tract, kidney and urinary tract, vascular heart and lungs. Crohn's Disease Symptoms Diarrhea Abdominal pains Intestinal blockages Fever Fatigue Loss of appetite and weight loss Still feeling full after using the toilet Frequent toileting is one of the early symptoms of Crohn's disease. Insomnia Diagnostic Methods Crohn's Disease Causes Immune system: It is possible for a virus or bacteria to trigger Crohn's disease; however, scientists have yet to identify such a trigger. When your immune system tries to fight off the invading microorganism, an abnormal immune response can cause the immune system to attack cells in the digestive tract as well. Heredity: Crohn's disease is more common in people with a family history of the same disease, so genes may play a role in the occurrence of the disease. Crohn's Disease Diagnostic Methods Blood analysis stool analysis Stomach, small and large intestine films Colonoscopy and endoscopy CT and MRI images Crohn's disease can occur at any age, but it usually occurs when the disease is young. Most people who develop Crohn's disease are diagnosed before they reach the age of about 30. You are at higher risk for the disease if you have a first-degree relative with the disease, such as a parent, sibling, or child. About 1 in 5 people with Crohn's disease have a family member with the disease. Facts About Crohn's Disease Treatment Options for Crohn's Disease Drug Therapy Steroid medications: These are medications that reduce inflammation in the digestive system. More information Surgical Treatment Many people with Crohn's disease may require surgical treatment. More information Crohn's Disease Diet In general, the patient is given a diet that is high in energy, high in protein, low in fiber, low in fat, and rich in vitamins and minerals. More information Transcutaneous Vagus Nerve Stimulation (tVNS) tVNS-L ® reduces inflammation in the intestine, allowing the intestine to perform its function more healthily. More information Contact us

tVNS E - İlaca Dirençli Epilepsi için Ameliyatsız Tedavi. İlacın yeterli olmadığı durumlarda vagus sinir stimulasyonu tVNS E, dirençli epilepsi ve major depresyon tedavisinde kullanılan dünyanın tek onaylı non-invazif vagus terapi cihazıdır insomnia Symptoms, Causes and Diagnostic Methods Insomnia Symptoms Difficulty falling asleep, waking up before expected, Not feeling fresh after sleep, Being angry and aggressive, Feeling tired and sluggish during the day, Difficulty with coordination and focus, Having difficulty remembering events, Being sleepy during the day, Worrying about sleep, Increase in the number of errors and accidents, Hyperactivity, Mood disorders, Anxiety and depression. Causes of Insomnia Stress Environmental disturbances (noise, light, or extreme heat/cold) Disruption of normal sleep patterns (Travel or a newborn baby) Jetlag after travel Medication use for various ailments The cause of the emergence of chronic insomnia. Unlike acute insomnia chronic diseases can also cause mental tension. Asthma chronic body aches heart palpitations chronic stress Depression drug use emotional or physical discomfort Thyroid diseases psychological reasons Insomnia Diagnostic Methods He or she may perform a physical exam to look for signs of medical problems that may be related to insomnia. While investigating the underlying physical diseases that may cause insomnia, it is also investigated whether there is a problem with the thyroid. If deemed necessary, reports of high-resolution imaging methods such as MRI may be requested. For a definitive diagnosis of insomnia, the doctor may request a chart of one or two weeks of sleep patterns or an overnight follow-up at the patient's sleep clinic. Thus, how long you stay awake at night, breathing movements, brain waves and body activities can be monitored and recorded. People with Insomnia Researchers state that 30% to 40% of adults try to cope with insomnia every year. According to the National Sleep Epidemiology Survey (TAPES) in Adults in Turkey, the incidence of insomnia is 15% (Male: 10.5%, Female: 20.2%). Contact us

tVNS E - İlaca Dirençli Epilepsi için Ameliyatsız Tedavi. İlacın yeterli olmadığı durumlarda vagus sinir stimulasyonu tVNS E, dirençli epilepsi ve major depresyon tedavisinde kullanılan dünyanın tek onaylı non-invazif vagus terapi cihazıdır Cognitive Impairment Symptoms, Causes and Diagnostic Methods Cognitive Disorder Symptoms Forgetfulness Lack of attention Excitement Unrest Speech difficulties Sleep disorder Causes of Cognitive Impairment Although the exact cause of cognitive impairment is not known exactly, the person's predisposition to Alzheimer's and dementia causes this disease. The following situations may also be the cause of cognitive impairment; Thyroid, kidney, or liver problems Depression, anxiety and stress Conditions that affect blood flow in the brain Vitamin B12 deficiency Cognitive Disorder Diagnostic Methods The diagnosis of cognitive disorder is made by neurology and psychiatry specialists. At this stage, it is very important to be accompanied by someone who knows and observes the patient closely. People with Cognitive Disorder The incidence in people over the age of 65 is around 15-20%. People with cognitive impairment are likely to progress to Alzheimer and dementia. However, cognitive impairment may not always be progressive. Contact us

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Transkutanöz Vagus Sinir Stimülasyonu (tVNS), vagus sinirine bir kulakluk yardımıyla elektriksel uyarılar verilmesini içeren tıbbi bir tedavidir . Dirençli epilepsi, kronik migren ve ilaca dirençli depresyon için etkili bir tedavi olarak kullanılır. What is Vagus Nerve? Discover The vagus nerve is the longest cranial nerve in the body. It comes from the Latin word, vagus, for “wandering.” That’s because it wanders throughout your body, with wide distribution connecting the brainstem to the body. Only mammals have this nerve. The vagus nerve serves as the body's superhighway, carrying information between the brain and the internal organs and controlling the body's response in times of rest and relaxation. It helps the immune system and inflammation response to disease. It has four main functions: sensory, special sensory, motor and parasympathetic. The vagus nerve also manages fears and sends information from the gut to the brain, which is linked to dealing with stress, anxiety, and fear–hence the saying, ‘gut feeling'. Historical Development of Vagus Nerve Stimulation Epilepsy has existed in human history with the first record found in a Babylonian text written 4000 years ago, and humanity has sought a cure for this disease for centuries. With the emergence of neurology in the 19th century, the mechanism between the nervous system and epilepsy was tried to be solved and the first vagus nerve stimulation was tried by a New York neurologist in the early 1880s. Over the next 100 years, the effects of vagus nerve stimulation were first investigated in animal experiments, then in humans, and in 1996, the vagus nerve was surgically implanted into the body and become an invasive stimulation option. At the beginning of the 2000s, for eliminating the side effects of invasive VNS, scientists tried to find out ways to stimulate the vagus nerve non-invasively, and by 2010 these studies were concluded successfully. Our first generation device, Nemos, was approved in 2010 for the treatment of epilepsy and depression, and Vitos in 2012 for the treatment of pain and migraine, as the first medically approved non-invasive vagus nerve stimulation treatment in the world. Our 2nd generation device, tVNS-L, has been approved in 2021, and has become a treatment option used in many neurodegenerative diseases. Vagus Nerve Stimulation Effect Overview Regulation of neurotransmitter release Increase in parasympathetic activity Increase in brain neuroplasticity Reducing inflammation Increasing the secretion of serotonin and increasing the mood What Are the Effects of Vagus Nerve Stimulation? Stimulation of the vagus triggers regulatory mechanisms in the nervous, immune, autonomic, endocrine, cardiorespiratory, and gastrointestinal systems. Clinical studies on the vagus nerve have shown that the activity in this nerve is closely related to epilepsy, depression, migraine, headache, inflammatory bowel disease, Alzheimer's, arthritis and many other common disorders by activating the parasympathetic nervous system in the brain and increasing the secretion of neurotransmitters in special regions of the brain. shows. Vagus nerve stimulation therapies are approved by FDA in the USA and CE in Europe for use in treatments such as mood improvement, pain relief, sleep improvement, memory enhancement and anxiety reduction. Research continues on the effects of neuroplasticity as well as its cardiac and inflammatory properties. Contact us

tVNS E - İlaca Dirençli Epilepsi için Ameliyatsız Tedavi. İlacın yeterli olmadığı durumlarda vagus sinir stimulasyonu tVNS E, dirençli epilepsi ve major depresyon tedavisinde kullanılan dünyanın tek onaylı non-invazif vagus terapi cihazıdır EPILEPSY Breakthrough Technologies for Life What is Epilepsy? Epileptic seizure (or seizure) is a clinical condition that occurs when the normal activity of the brain is disrupted as a result of temporary abnormal electrical activity in nerve cells. Epilepsy, also known as "Sara Disease" among the people, manifests itself with epileptic seizures. Epilepsy is a chronic disease. It develops in people who have brain damage during or after birth for any reason. It is a disease seen in 1% of the population in the world and in our country, and about 70% of these patients can be treated with epilepsy drugs called antiepileptic. More than 30 percent of all epileptic patients continue to have seizures despite taking appropriate medications (anticonvulsants) for epileptic seizures, a condition called refractory epilepsy. Several treatment options are available for patients in this condition. SYMPTOMS Read more REASONS Read more WHO IS SEEN IN Read more DIAGNOSTIC METHODS Read more Types of Epilepsy Doctors have described more than 30 different types of seizures, ranging from very brief shifts of attention to prolonged seizures. The frequency of seizures is also variable, with some patients having less than one seizure per year, while others may experience multiple seizures per day. Seizures are generally divided into two main groups (partial or generalized seizures) depending on the area of abnormal electrical activity in the brain. Partial Seizures: Partial seizures begin and affect only one part of the brain. Also known as 'focal', these seizures can be seen in the following ways. Secondary Generalized: A seizure that begins as a partial seizure and spreads to the rest of the brain, becoming a generalized seizure. Complex: The person experiences changes in consciousness and loss of consciousness, which causes confusion. The person may experience a dreamlike state or exhibit strange and repetitive behaviors such as emotional outbursts or blinks and tics. Generalized Seizures: Generalized seizures occur as a result of abnormal activity in both halves of the brain simultaneously. Absence Seizures: Associated with a shift of consciousness in which the person seems to be immersed in the void. This condition usually begins in childhood and is confused with attention deficit. Simple seizures: Despite seizure activity, the person is conscious and remains aware of those around them. An abnormal twitching, lethargy, sweating, drowsiness, nausea, disturbances of perception and memory, and a feeling of 'deja vu' may occur. Treatment Options for Drug-Resistant Epilepsy Epilepsy Surgery It is the surgical intervention of areas of the brain that cause epileptic seizures and do not perform their normal functions. More information Invasive Vagus Nerve Stimulation (iVNS) A pacemaker is surgically implanted under the chest and an electrode is placed in the vagus nerve in the neck. The electrodes stimulate the vagus nerve near the carotid artery at regular intervals. More information Antiepileptic Drugs They are designed to correct the chemical imbalance in brain cells that causes seizures. These medications work in different ways, some of which are not yet fully understood. More information Transcutaneous Vagus Nerve Stimulation (tVNS) It is a treatment option that stimulates the centers in the brain by stimulating the vagus nerve with the help of an electrode attached to the ear. More information WE DESIGN THE MEDICAL TECHNOLOGIES OF THE FUTURE Contact us

tVNS E - İlaca Dirençli Epilepsi için Ameliyatsız Tedavi. İlacın yeterli olmadığı durumlarda vagus sinir stimulasyonu tVNS E, dirençli epilepsi ve major depresyon tedavisinde kullanılan dünyanın tek onaylı non-invazif vagus terapi cihazıdır AUTISM Symptoms, Causes and Diagnostic Methods Autism Symptoms Lack of social communication Can't make eye contact They do not react to what is said lack of speech They do not feel danger and fear They don't look back when their name is called They tend to walk on their toes. Sensitivity to light and sound Causes of Autism Although the exact cause of autism has not been found, it is stated by experts as a genetic disease. Psychological problems experienced by the mother before birth, gene mutation, alcohol and cigarette use increase the risk of the baby having autism. Autism Diagnostic Methods Early diagnosis is very important in autism symptoms that show limited and repetitive behaviors. It is necessary to get help by monitoring the child's behavior by a specialist physician. Autism diagnosed at the age of 2 to 4 years has high reliability levels. Who Has Autism visible Autism is more common in boys than girls. Approximately 3.6% of boys and 1.3% of girls between the ages of 3 and 17 have autism spectrum. According to the data released by the World Health Organization in 2021, one out of every 160 children in the world is diagnosed with autism. Contact us

tVNS E - İlaca Dirençli Epilepsi için Ameliyatsız Tedavi. İlacın yeterli olmadığı durumlarda vagus sinir stimulasyonu tVNS E, dirençli epilepsi ve major depresyon tedavisinde kullanılan dünyanın tek onaylı non-invazif vagus terapi cihazıdır Epilepsy Symptoms, Causes and Diagnostic Methods Epilepsy Symptoms Since epilepsy is a dysfunction that occurs in the brain, the symptoms of epilepsy may vary depending on the function of the affected area of the brain. We can list some symptoms of the disease as follows: Sudden contractions in the body Loss of consciousness Very rapid nodding Uncontrollable shaking in arms and legs wink quickly Looking at a fixed point Being unable to react to sounds or speech for a short time Fear, anxiety or deja vu etc. psychological symptoms Epilepsy Causes Epilepsy is a condition that can have many causes and can occur at any age. It usually starts in childhood. Any disease that affects the brain can cause epileptic seizures. Infections in the womb Birth traumas, lack of oxygen during birth Head injury Genetic and metabolic diseases High fever diseases, Excessive low blood sugar, Intracranial tumors, Brain inflammations. Paralysis Brain tumor Developmental brain malformations Brain infections such as meningitis can lead to epilepsy, Vascular abnormalities, especially in the brain vessels of individuals in the advanced age group, Some epilepsies occur as a result of an electrical activity spreading from this region as a result of disruption in a certain region of the brain. Epilepsies resulting from brain tumors and traumas can be given as examples for this situation. In some types of epilepsy, there is no damage in a single area. An epileptic seizure begins suddenly in the entire brain. Childhood-onset epilepsies are usually of this type. Types of epilepsy also differ from person to person, and this situation also affects the causes and causes of epilepsy. Because not every epilepsy person shows the same symptoms. Epilepsy Diagnostic Methods Imaging methods are one of the primary methods used in the diagnosis of epilepsy. (EEG), (MR) and computed tomography are among the most commonly used imaging methods. EEG, which indicates the electrical activity of the brain, is especially important in the diagnosis of epilepsy. Thanks to EEG, regions of the brain with uncontrolled bioelectrical activity are detected. Whether there is any structural problem that causes seizures is understood by MRI and tomography. If required by specialist physicians, blood and urine tests are also performed. For the diagnosis of epilepsy, the patient's medical history, frequency and severity of seizures, and symptoms are among the points that physicians pay attention to. Sometimes, extreme stress, fatigue, emotional and hormonal changes can also cause seizures. In this sense, not every seizure indicates epilepsy. Physicians can diagnose after listening to patients' stories. People with epilepsy About 50 million people in the world have epilepsy, making epilepsy one of the most common neurological diseases worldwide. It can be seen at any age, although it is more common in childhood and over 65 years of age. Epilepsy can occur in both sexes at any age and in any geographic area. Most people are likely to have an epileptic seizure once in their lifetime. People with more than one epileptic seizure are considered epileptic and should be treated with appropriate medications. In Turkey, 7 out of every 1000 people suffer from epilepsy. Contact us

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